Which of the following would be the correct complimentary DNA sequence for the following: 5'-TATATGGCGATATAGGG-3'

Question

Which of the following would be the correct complimentary DNA sequence for the following:   5'-TATATGGCGATATAGGG-3'

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Question restatement: Which of the following would be the correct complimentary DNA sequence for the following:  5'-TATATGGCGATATAGGG-3'?

Option analysis:
- Option 1: 3'-ATATACCGCTATATCCC-5
  This matches the expected complementary DNA strand. Using base-pair rules (A pairs with T, T with A, G with C, C with G) and keeping the anti-parallel orientation, the 3'→5' strand complementary to 5'-TATATGGCGATATAGGG-3' is indeed 3'-ATATACCGCTATATCCC-5. Therefore, this option is correct.
- Option 2: 5'-ATATACCGCTATATCCC-3'
  This presents the complementary sequence in the same 5'→3' orientation as the top strand, which would be incorrect because the complementary strand must run opposite orientation (3'→5') relative to the given strand. Thus, this is not the correct orientation.
- Option 3: 3'-AUAUACCGCUAUAUCCC-5
  This uses uracil (U) instead of thymine (T), which is characteristic of RNA rather than DNA. Since the question specifies DNA and asks for a complementary DNA sequence, this option is not appropriate.

In summary, the correct approach is to apply base-pairing rules to generate the anti-parallel complementary DNA strand, which yields 3'-ATATACCGCTATATCCC-5. The other options either present the wrong orientation, represent RNA, or use incorrect nucleotide characters for DNA.

SMC 2025 Spr - BIOL 3 (1286,1288) - Fundamentals of Biology (G) Quiz 9 DNA

Which of the following would be the correct complimentary DNA sequence for the following: 5'-TATATGGCGATATAGGG-3'

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