Which of the following correctly represents the flow of genetic information according to the central dogma of molecular biology? (without the exceptions)

Question

BlackTom AI · Accepted Answer

Let’s analyze each option in light of the central dogma of molecular biology, which describes the flow of genetic information as DNA transcribed to RNA and then translated into protein.
Option 1: 'DNA → Protein' This skips the RNA transcription and translation steps. In reality, information is not directly transferred from DNA to protein without the intermediate RNA, so this representation is incomplete and misleading.
Option 2: 'Protein → DNA → RNA' This sequence starts with a protein and implies information flows backward from protein to DNA to RNA, which contradicts the established direction of information transfer in biology. The central dogma does not describe proteins directing DNA or RNA synthesis as the primary flow.
Option 3: 'DNA → RNA → Protein' This sequence matches the canonical flow: DNA is transcribed into messenger RNA, and the RNA is translated into a polypeptide/protein. It captures both the transcription and translation steps that encode and express genetic information.
Option 4: 'RNA → DNA → RNA' This implies RNA makes DNA and then RNA again, which would be reverse transcription and subsequent transcription, not part of the standard central dogma (and is not the general, exception-free flow). It misrepresents the unidirectional information pathway from DNA to RNA to protein.
In summary, the third option aligns with the core concept that information stored in DNA is transcribed into RNA and then translated into protein, while the other options disrupt or reverse this established sequence.

Which of the following correctly represents the flow of genetic information according to the central dogma of molecular biology? (without the exceptions)

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Which of the following correctly represents the flow of genetic information according to the central dogma of molecular biology? (without the exceptions)

View Explanation

Log in for full answers

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Question at position 4 which answer is the best depiction of the normal flow of genetic information? Protein ⟶DNA ⟶ RNARNA ⟶DNA ⟶ ProteinDNA ⟶RNA ⟶ ProteinProtein ⟶RNA ⟶ DNAClear my selection

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DNA is into RNA, which is into protein.