Hemidesmosomes are present on the basal surface of stratified squamous epithelim, where the epithelial cells are adjacent to a basla lamina and the underlying connective tissue.

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BlackTom AI · Accepted Answer

The statement concerns the presence and location of hemidesmosomes in stratified squamous epithelium.
Option analysis:
Option 1: True. Hemidesmosomes are junctional complexes that mediate adhesion between epithelial cells and the basement membrane (basal lamina). They are typically located on the basal surface of epithelial cells, anchoring the cells to the underlying basement membrane and ultimately to the connective tissue. In stratified squamous epithelium, the basal layer contacts the basement membrane and the underlying stroma, and hemidesmosomes help secure these basal cells to the basement membrane, which aligns with the described scenario.
Option 2: False. This would imply that hemidesmosomes do not exist on the basal surface or are not involved in attaching epithelium to the basement membrane. However, the well-established role of hemidesmosomes is precisely to mediate adhesion from the basal cell surface to the basement membrane, so this option contradicts fundamental cell biology.
In summary, the statement correctly captures the typical localization and function of hemidesmosomes in stratified squamous epithelium, by situating them at the basal aspect where cells interact with the basal lamina and underlying connective tissue.

AVBS2005 (ND) Cytology II

Hemidesmosomes are present on the basal surface of stratified squamous epithelim, where the epithelial cells are adjacent to a basla lamina and the underlying connective tissue.

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