If A, B, and C represent G1, S, and G2, respectively, then which phase of the cell cycle would you predict to last the longest in duration? Use the data shown in the left panel (Cells without treatment graph) to answer this question.

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The question asks us to determine which phase of the cell cycle lasts the longest, given that A, B, and C correspond to G1, S, and G2 respectively, and we should use the left panel data (Cells without treatment graph).
Option S: DNA synthesis occurs during the S phase, but in many cell populations, S is shorter than G1 because cells spend more time growing and preparing for DNA replication in G1 than actually replicating DNA in S.
Option G0: G0 is a quiescent state where cells are not actively cycling. While some cells can enter G0, the question is about the standard cell cycle phases and the graph is labeled in terms of G1, S, and G2. If many cells are still cycling, G0 would not represent the majority duration of the main cycle phases.
Option G2: G2 is the second gap after DNA synthesis and before mitosis. It is typically shorter than G1 because the bulk of time in the cycle is spent preparing for and executing cell growth during the G1 phase, with the subsequent steps taking comparatively less total time.
Option G1: G1 is the first gap phase where cells grow, synthesize proteins, and prepare for DNA replication. In many datasets and standard interpretations of the cell cycle, G1 is the longest phase because it encompasses substantial cell growth and regulatory decisions before committing to DNA synthesis in S.
In light of the labeling that A = G1, B = S, and C = G2, and given common observations from untreated cell populations where G1 consumes the greatest share of total cycle time, the longest-duration phase corresponds to G1.
Therefore, among the options, the one that aligns with the data and typical cell-cycle timing is G1.

Bio 93 Section CDE 2025 Midterm 2- Section E

If A, B, and C represent G1, S, and G2, respectively, then which phase of the cell cycle would you predict to last the longest in duration? Use the data shown in the left panel (Cells without treatment graph) to answer this question.

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