A new cholesterol treatment is being tested during a clinical trial with over 3,000 patients. The patients in the study don’t know if they are receiving the new treatment or a placebo. The people testing the new treatment do know what participants are receiving. This is an example of:

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The scenario describes a trial in which the participants do not know whether they receive the new treatment or a placebo, while the researchers conducting the study do know. This arrangement is characteristic of a single-blind study, where only one party (usually the participants) is unaware of treatment allocation.

Option 1: Double blind study. In a double-blind study, both participants and researchers are unaware of which treatment each participant is receiving. Since the text states that the people testing the new treatment do know what participants are receiving, this is not a double-blind design, making this option incorrect.

Option 2: Single blind study. This matches the described setup: participants are unaware of their allocation, while researchers are aware. This is the correct interpretation for the given scenario.

Option 3: Case series. A case series is a descriptive study that follows a group of patients with a particular condition without a control group or randomization. The current description involves a controlled trial with placebo, not a case series, so this is incorrect.

Option 4: Ecologic study. An ecologic study examines data at the population or group level rather than individuals, often looking at associations between exposure and outcome across groups. The described trial is individual-level randomization with blinding, so this option does not fit and is incorrect.

PUBHEPI 2410 AU2025 (1751) Quiz Module 9: Experimental studies

A new cholesterol treatment is being tested during a clinical trial with over 3,000 patients. The patients in the study don’t know if they are receiving the new treatment or a placebo. The people testing the new treatment do know what participants are receiving. This is an example of:

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