Biosafety Levels (BSLs) are exactly equivalent to the Biosafety Risk Groups as classified by World Health Organisation (WHO). Is the above statement true or false?

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Question restatement: The prompt asks whether Biosafety Levels (BSLs) are exactly equivalent to the Biosafety Risk Groups as classified by the World Health Organization (WHO), and to identify true or false.
Option 1: 'True' — This is not accurate. BSLs are defined as containment levels (BSL-1 through BSL-4) with specific laboratory practices, facilities, and equipment, primarily by organizations like the CDC/NIH in the United States. WHO defines Biosafety Risk Groups (RGs) for microorganisms (RG1 to RG4) based on their inherent risk to humans and the environment. These two systems describe related but not identical concepts, and their criteria, scales, and implementation details do not map one-to-one. Saying they are 'exactly equivalent' ignores differences in scope (facilities vs. organism risk), criteria, and the way each system guides safety practices. A common misconception is treating containment levels and risk groups as interchangeable, which this option incorrectly asserts.
Option 2: 'False' — This accurately reflects the relationship. While BSLs and WHO Risk Groups are related in that higher RGs generally call for higher containment levels, the mapping is not exact or universally fixed. BSLs depend on laboratory practices, facilities, and equipment, whereas RGs depend on characteristics of the organism and its risk profile. Consequently, equivalence would oversimplify and misrepresent how these frameworks operate across different settings and organisms, making the statement false.
Additional note: Understanding both frameworks requires recognizing that they serve complementary purposes—BSLs focus on the containment measures in a given laboratory setting, while RGs focus on the inherent risk posed by the biological agents themselves. This distinction explains why the assertion of exact equivalence is misleading.

SD_GEN_SFTY_BME_FYP_2024 LAB06: Biological Safety - Quiz

Biosafety Levels (BSLs) are exactly equivalent to the Biosafety Risk Groups as classified by World Health Organisation (WHO). Is the above statement true or false?

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