Which of the following is a true statement regarding the function of creatine phosphate (CrP)?

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The question asks: Which of the following is a true statement regarding the function of creatine phosphate (CrP)?

First, note that the provided answer options list is empty, so we cannot compare multiple statements. Given the single listed option, we will evaluate it on its own merits and explain the core function of creatine phosphate.

Option provided: 'CrP rapidly replenishes ATP.'

Creatine phosphate serves as a rapid reserve of high-energy phosphate groups. During short, intense exercise, CrP donates its phosphate to adenosine diphosphate (ADP) to quickly form adenosine triphosphate (ATP) via the reaction CrP + ADP → Cr + ATP, catalyzed by the enzyme creatine kinase. This provides an immediate but short-lived boost of ATP, typically sustaining maximal effort for roughly 5–15 seconds depending on training and muscle economy. This mechanism is distinct from slower pathways like glycolysis or oxidative phosphorylation, which generate ATP more gradually but sustain activity longer.

Why this statement is true: The defining feature of CrP is its role as a rapid ATP buffer, enabling immediate energy resynthesis during sudden bursts of activity when ATP demand spikes. The reaction is designed specifically for speed rather than volume, which is why CrP stores are limited and become depleted quickly with ongoing high-intensity work.

Why the idea might be misinterpreted if someone thought CrP does more than this: Creatine phosphate does not directly supply energy for prolonged activities; its contribution is transient because the CrP reservoir is limited. Additionally, CrP does not replenish ATP via other pathways; its main function is the immediate transfer of a phosphate to ADP to reform ATP. Other energy systems (phosphocreatine rephosphorylation, glycolysis, oxidative phosphorylation) contribute ATP over longer times but are not what CrP is primarily known for.

If other answer options were present, we would assess each against this mechanism: any option claiming CrP provides long-term ATP supply or acts as a direct energy source beyond rapid ATP replenishment would be inaccurate. Any claim contradicting the creatine kinase–catalyzed transfer of phosphate would also be incorrect. Since no alternative options are provided, we focus on this core function and its temporal limitation: CrP rapidly replenishes ATP but only for a brief window at the start of high-intensity demand.

NUTR 406 B S1. Creatine supplementation

Which of the following is a true statement regarding the function of creatine phosphate (CrP)?

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